Use caution when prescribing GaviLyte-G for patients at increased risk of arrhythmias (e.g., patients with a history of prolonged QT, uncontrolled arrhythmias, recent myocardial infarction, unstable angina, congestive heart failure, or cardiomyopathy). There have been rare reports of serious arrhythmias associated with the use of ionic osmotic laxative products for bowel preparation. In addition, use caution when prescribing GaviLyte-G for patients who have conditions, or who are using medications, that increase the risk for fluid and electrolyte disturbances or may increase the risk of adverse events of seizure, arrhythmias, and renal impairment Cardiac Arrhythmias Fluid and electrolyte abnormalities should be corrected before treatment with GaviLyte-G. Fluid and electrolyte disturbances can lead to serious adverse events including cardiac arrhythmias, seizures and renal impairment. If a patient develops significant vomiting or signs of dehydration including signs of orthostatic hypotension after taking GaviLyte-G, consider performing post-colonoscopy lab tests (electrolytes, creatinine, and BUN) and treat accordingly. Use caution in patients with congestive heart failure when replacing fluids. Warnings and Precautions Serious Fluid and Serum Chemistry AbnormalitiesĪdvise patients to hydrate adequately before, during, and after the use of GaviLyte-G. Known allergy or hypersensitivity to any component of GaviLyte-G.Gastrointestinal (GI) obstruction, ileus, or gastric retention.GaviLyte-G is contraindicated in the following conditions: When made up to 4 liters volume with water, the solution contains PEG-3350 17.6 mmol/L, sodium 125 mmol/L, sulfate 40 mmol/L, chloride 35 mmol/L, bicarbonate 20 mmol/L and potassium 10 mmol/L. Dosage Forms and Strengthsįor oral solution: One 4 liter jug with powder for reconstitution with water.Įach 4 liter jug contains: polyethylene glycol 3350 236 g, sodium sulfate (anhydrous) 22.74 g, sodium bicarbonate 6.74 g, sodium chloride 5.86 g, potassium chloride 2.97 g. Continue drinking until the watery stool is clear and free of solid matter. The first bowel movements should occur approximately one hour after the start of GaviLyte-G administration. For NGT, rate is 20-30 mL per minute (1.2 – 1.8 liters per hour). Rapid drinking of each portion is preferred to drinking small amounts continuously. Adults: Instruct patients to drink a total of 4 liters at a rate of 240 mL (8 oz.) every 10 minutes, until 4 liters are consumed or the rectal effluent is clear.The solution is more palatable if chilled prior to administration. Instruct patients they may consume water or clear liquids during the bowel preparation and after completion of the bowel preparation up until 2 hours before the time of the colonoscopy. The following is the recommended dose of reconstituted GaviLyte-G solution for adults. After capping the container, shake vigorously several times to ensure that the ingredients are dissolved.The solution is clear and colorless when reconstituted to a final volume of 4 liters. Early in the evening prior to colonoscopy, fill the supplied container containing the GaviLyte-G powder with lukewarm water (to facilitate dissolution) to the 4 liter fill line.Take only clear liquids, but avoid red and purple liquids.On the day prior to the colonoscopy, instruct patients to: Administration Instructions Prior to Dosage GaviLyte-G is supplied with lemon flavor pack. The 4 liter reconstituted GaviLyte-G solution contains: 236 grams of polyethylene glycol (PEG) 3350, 22.74 grams sodium sulfate (anhydrous), 6.74 grams of sodium bicarbonate, 5.86 grams of sodium chloride, and 2.97 grams of potassium chloride. GaviLyte-G, supplied as a powder, must be reconstituted with water before its use it is not for direct ingestion. GaviLyte G Dosage and Administration Dosage Overview GaviLyte-G is indicated for bowel cleansing prior to colonoscopy and barium enema X-ray examination in adults. Expand Indications and Usage for GaviLyte G
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